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Freeze-dried rabies vaccine followed by death due to septic shock: a case report / 上海预防医学
Shanghai Journal of Preventive Medicine ; (12): 1206-1208, 2021.
Article in Chinese | WPRIM | ID: wpr-907117
ABSTRACT
ObjectiveTo analyze a case of death after inoculation of a freeze-dried rabies vaccine for human use so as to provide reference for the vaccination of the rabies vaccine and the process of investigation and diagnosis involving adverse events following immunization (AEFI) in the future. MethodsData on vaccination, clinical symptoms, treatments, investigation and diagnosis were collected and analyzed. ResultsRabies post-exposure prophylaxis and vaccination were in line with the protocols. On the 3rd day after the inoculation of the rabies vaccine, the patient developed fever, weakness, headachedizzinessdiarrhea and other symptoms. The white blood cell count and neutrophil count increased progressively. At about 17:00 on the same day, the patient suffered a sudden cardiac arrest and died clinically. Autopsy was not carried out. ConclusionThe cause of sepsis /septic shock of the patient is unknown. It is necessary to formulate detailed rabies immunization procedures as well as norms and expert consensus in the field of investigation and diagnosis of AEFI.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Practice guideline Language: Chinese Journal: Shanghai Journal of Preventive Medicine Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Practice guideline Language: Chinese Journal: Shanghai Journal of Preventive Medicine Year: 2021 Type: Article