Progress of enhancing the function of chimeric antigen receptor T-cells in replased/refractory B-cell malignancies / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 508-512, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-907206
ABSTRACT
When chimeric antigen receptor T cells (CAR-T) failed to treat relapsed and refractory B-cell malignancies, some researchers try to improve the efficacy by enhancing the function of CAR-T. It is a new hotspot of drug development and clinical research, and significant achievements have been made in this area recently. Multi-targeted CAR-T, lenalidomide, decitabine, programmed death 1 inhibitor and ibrutinib can all enhance the function of CAR-T. This article reviews the recent progress of enhancing the function of CAR-T in relapsed and refractory B-cell malignancies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2021
Type:
Article
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