Tumor microenvironment and immunotherapy of neuroblastoma / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 435-439, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-907253
ABSTRACT
Neuroblastoma(NB)is one of the most common malignant tumors in children.The prognosis of patients with high-risk NB remains poor despite intensive multimodal treatments including surgery, chemotherapy, radiation therapy and autologous hematopoietic stem cell transplantation.Recently, with good therapy results in hematological malignant tumors, more attention has been paid to immunotherapy for solid tumors such as NB.However, the efficacy of immunotherapy for NB is not as good as that for other hematological malignancies, which may be related to the complex tumor microenvironment(TME)of solid tumors.In order to better understand the direction and future application of immunotherapy in NB, we review TME and current immunotherapy for NB.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2021
Type:
Article
Similar
MEDLINE
...
LILACS
LIS