Mechanism of microglia involved in the pathophysiology of brain white matter hyperintensity / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 467-470, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-907350
ABSTRACT
As an important imaging marker of cerebral small vessel disease, white matter hyperintensity is closely associated with the clinical manifestations such as cognitive impairment, gait abnormalities, and urinary incontinence. Current studies have shown that the destruction of blood-brain barrier and inflammation response are the important pathophysiological mechanisms of white matter hyperintensity. As the most common immune cell in the inflammatory response of the central nervous system, microglia activation is the key to the occurrence and development of white matter hyperintensity. This article reviews the pathophysiological mechanisms of microglia involved in brain white matter hyperintensity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2021
Type:
Article
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