Meta-analysis of the effect on constipation patients under the interventions of exercise / 国际生物医学工程杂志

ABSTRACT

Objective:To systematically evaluate the effect of physical exercises on the treatment of constipation by Meta-analysis.Methods:Randomized controlled trials of the effects of physical exercises on constipation were retrieved in databases of CNKI, WanFangData, VIP, SinoMed, PubMed, Web of Science and Cochrane Library from inception to December 2020. According to the inclusion and exclusion criteria, two reviewers independently selected literature, extracted data. The quality of included literature was evaluated by referring to the Cochrane collaboration's tool. And then the funnel plot was used to evaluate the risk of bias of included literature. Revman 5.3 software was used to conduct meta-analysis.Results:A total of 12 clinical trials include 1 004 patients were involved based on the inclusion and exclusion criteria. The physical exercise group was subjected to physical exercise or added other conventional treatment, and the control group had no regular exercise or only conventional treatment during the test. The fixed effects model was employed. The total effect of the value of the merger was calculated, the combined OR(95% CI) was 4.75(3.47, 6.51). Compared with the control group, exercise significantly relieved the patient's constipation symptoms( Z=9.69, P<0.000 01). Funnel figure shows a basic symmetry, which indicated the publication bias is small. Conclusions:Physical exercise is beneficial to constipation should be encouraged.