Application of next-generation sequencing technology in pathogen detection of lower respiratory tract infection in children / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 1115-1118, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-907916
ABSTRACT
Next-generation sequencing (NGS), also known as high-throughput sequencing, is more efficient compared with Sanger sequencing that has become the standard method of clinical DNA sequencing, and can obtain a large amount of information in a relatively short time at a lower cost.NGS has broad prospects in such aspects as diagnosing the pathogen of lower respiratory tract infection in children, identifying the pathogen of cross-infection in hospital, drug resistance research and vaccine development.It is still worth conducting further studies on the approach to improve the specificity and sensitivity of diagnosis and to optimize NGS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Applied Clinical Pediatrics
Year:
2021
Type:
Article
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