Analysis of factors influencing the prognosis of thoracic ossification of ligamentum flavum and construction of related models / 中国医师进修杂志

ABSTRACT

Objective:To analyze the influencing factors of thoracic ossification of ligamentum flavum (TOLF) and to construct a predictive model.Methods:The clinical data of 138 patients who underwent TOLF surgery during February 2016 to February 2019 in Fengjie County People′s Hospital were retrospectively analyzed. All patients were followed up 6 months after the operation to evaluate the prognosis. Patients whose efficacy evaluated as "fair" or "poor" were included in the poor prognosis group (35 patients), and those whose efficacy evaluated as "excellent" "or "good" were included in the good prognosis group (103 patients). The clinical data of the two groups of patients were collected, and the risk factors affecting the prognosis of patients undergoing TOLF surgery were analyzed by multivariate Logistic regression method. A prediction model was constructed and it′s effect was verified finally.Results:Multivariate Logistic regression analysis showed that complications of dural sac bone, T 2 -weighted intramedullary high signal, spinal canal area residual rate, postoperative cerebrospinal fluid leakage and course of disease were risk factors for poor prognosis of TOLF surgery ( P<0.05). Prediction model P = 1/ (e