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A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children
Allergy, Asthma & Immunology Research ; : 535-540, 2016.
Article in English | WPRIM | ID: wpr-90954
ABSTRACT

PURPOSE:

Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children.

METHODS:

We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea.

RESULTS:

A total of 991 cases (mean age=5.89±5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes.

CONCLUSIONS:

The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Arachis / Triticum / Medical Records / Epidemiology / Retrospective Studies / Seafood / Contrast Media / Fagopyrum / Juglans / Milk Type of study: Observational study / Prognostic study Limits: Child / Humans / Male Country/Region as subject: Asia Language: English Journal: Allergy, Asthma & Immunology Research Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Arachis / Triticum / Medical Records / Epidemiology / Retrospective Studies / Seafood / Contrast Media / Fagopyrum / Juglans / Milk Type of study: Observational study / Prognostic study Limits: Child / Humans / Male Country/Region as subject: Asia Language: English Journal: Allergy, Asthma & Immunology Research Year: 2016 Type: Article