Advances in the treatment of ovarian cancer with BRCA gene mutation / 中国综合临床
Clinical Medicine of China
;
(12): 470-473, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-909780
ABSTRACT
Ovarian cancer is the most fatal malignant tumor in female reproductive system tumors.In most women, it is diagnosed in a late stage, which largely leads to the poor prognosis of ovarian cancer.Breast cancer susceptibility gene (BRCA) is an important DNA homologous repair gene, which plays a major role in the normal cellular DNA repair mechanism.Its mutation will lead to homologous recombination defects, which will affect the stability of the genome and lead to occurrence of tumors.In recent years, BRCA genetic testing has become a key step in the risk assessment, prognosis, treatment and prevention of ovarian cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Risk factors
Language:
Chinese
Journal:
Clinical Medicine of China
Year:
2021
Type:
Article
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