Case series of patients with cholesterol crystal embolism syndrome that mimics systemic vasculitis / 中华风湿病学杂志
Chinese Journal of Rheumatology
; (12): 597-604,C9-1, 2021.
Article
in Zh
| WPRIM
| ID: wpr-910207
Responsible library:
WPRO
ABSTRACT
Objective:To improve the awareness of cholesterol crystal embolism syndrome (CCE) inrheumatologists.Methods:The clinical characteristics of 40 Chinese CCE patients admitted to our department (one case) were summarize and in the literature (thirty-nine cases) were reviewed.Results:Among these 40 patients, 87.5%(35/40) were male and the mean age was (68±6) years. All patients suffered from athero-sclerosis and 87.5%(35/40) of them had precipitating factors such as endovascular intervention, vascular surgery, anticoagulant, or thrombolytic therapy. The clinical manifestations included renal insufficiency (90.0%, 36/40), blue toe syndrome (82.5%, 33/40), ulceration or gangrene (25.0%, 10/40), and livedo reticularis (15%, 6/40). Acute phase reactant was tested in 25 cases, of whom 84.0%(21/25) showed elevated C-reactive protein (CRP) and 56.0%(14/25) showed elevated erythrocyte sedimentation rate (ESR).Conclusion:Rheumatologists should be alert that CCE is one of the differential diagnosis of systemic vasculitis, especially for patients with severe atherosclerosis.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Rheumatology
Year:
2021
Type:
Article