Research progress in insufficient fracture after pelvic radiotherapy / 中华放射医学与防护杂志
Chinese Journal of Radiological Medicine and Protection
;
(12): 469-474, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-910341
ABSTRACT
Pelvic radiotherapy is a way for treatment of most pelvic tumors, of which the pelvic insufficiency fracture (PIF) is a long-term complication. In this review, research progress of pelvic insufficiency fracture is summarized and discussed. The pathogenesis of PIF is mainly about inhibition of osteoblasts and the risk factors of PIF include old age, postmenopausal status, absence of hormonal replacement therapy, high number of births, smoking history, low body mass index (BMI), concurrent rheumatoid arthritis, concurrent diabetes mellitus, intracavitary brachytherapy of the high dose rate (HDR-ICBT), high dose of radiotherapy, etc. Effective drugs for prevention or treatment of PIF have not been found yet. Delayed diagnosis and misdiagnosis of PIF can cause serious consequences. As a result, further studies are needed to guide clinical work.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Radiological Medicine and Protection
Year:
2021
Type:
Article
Similar
MEDLINE
...
LILACS
LIS