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The progress on the mechanism of NLRP3 inflammasome in renal ischemia-reperfusion injury / 中华泌尿外科杂志
Chinese Journal of Urology ; (12): 554-558, 2021.
Article in Zh | WPRIM | ID: wpr-911071
Responsible library: WPRO
ABSTRACT
Renal ischemia-reperfusion injury often occurs during operations that need to block the blood supply of the kidneys. It is an important pathophysiological process that affects the recovery of kidney function and causes acute renal failure. Activated NLRP3 inflammasome can mediate the maturation and release of a variety of pro-inflammatory factors, and participate in the inflammatory response in renal ischemia-reperfusion injury, thereby regulating body inflammation and related cell functions. This article summarized how NLRP3 inflammasome mediated the occurrence of inflammation in renal ischemia reperfusion injury, and further provied a new basis for the prevention and treatment of renal ischemia-reperfusion injury.
Key words
Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Journal of Urology Year: 2021 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Journal of Urology Year: 2021 Type: Article