Effect of diabetes mellitus on pulmonary uptake of sevoflurane / 中华麻醉学杂志
Chinese Journal of Anesthesiology
;
(12): 1227-1229, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-911347
ABSTRACT
Objective:
To investigate the effect of diabetes mellitus on pulmonary uptake of sevoflurane.Methods:
Twenty patients with type 2 diabetes mellitus, aged 40-64 yr, with body mass index of 18.5-22.9 kg/m 2, of American Society of Anesthesiologists physical status Ⅰ or Ⅱ, undergoing elective surgery with general anesthesia, served as diabetes group (group D). Twenty non-diabetic patients matched by age, gender and surgery were selected as control group (group C). After anesthesia induction and tracheal intubation, sevoflurane was inhaled at a concentration of 2% (oxygen flow 2 L/min). The inhaled concentration (Fi) and exhaled concentration (Fa) at 1, 3, 5, 10, 15, 20 and 30 min of inhalation of sevoflurane were recorded, and the Fa/Fi ratio was calculated.The time required for the Fa/Fi ratio to reach 0.7 was recorded.Results:
Compared with group C, the Fa/Fi ratio was significantly increased at each time point, and the time required for the Fa/Fi ratio to reach 0.7 was shortened in group D ( P<0.05).Conclusion:
Diabetes mellitus can reduce pulmonary uptake of sevoflurane in the patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Anesthesiology
Year:
2021
Type:
Article
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