Progress on diagnosis and treatment of pregnancy with pulmonary hypertension associated with congenital heart disease / 中华围产医学杂志

ABSTRACT

Pulmonary hypertension associated with congenital heart disease in pregnancy is a complex condition with challenges for both diagnosis and treatment. Echocardiography is the most common method to detect pulmonary arterial pressure and has a high diagnostic value in pulmonary hypertension. Right cardiac catheterization is not a routine examination in pregnancy. Sildenafil may effectively improve the left ventricular ejection fraction and blood oxygen saturation of patients. Prostaglandins have good therapeutic efficacy in patients with pulmonary hypertension and cardiac function grade Ⅲ-Ⅳ. Surgical intervention can be considered when drug therapy fails. The risk factors for death in patients with this disease are inadequate prenatal examination, combined with moderate to severe pulmonary hypertension, Eisenmenger syndrome, cardiac function grade Ⅲ-Ⅳ, and severe hypoxemia. Women with pulmonary hypertension associated with congenital heart disease are carring higher risk in pregnancy, and requiring individualized treatment and multidisciplinary management.