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Progress on pravastatin and its safety in prevention and treatment of preeclampsia / 中华围产医学杂志
Chinese Journal of Perinatal Medicine ; (12): 862-867, 2021.
Article in Chinese | WPRIM | ID: wpr-911984
ABSTRACT
Preeclampsia is the main cause of poor maternal-fetal outcomes. A series of cell and animal experiments, and a small number of clinical studies have shown that pravastatin can prevent and treat preeclampsia by regulating angiogenesis, increasing the expression of heme oxygenase, and stimulating the production of nitric oxide without any reported adverse effects during pregnancy. We review the latest progress on the mechanism, effect, and safety of pravastatin in the prevention and treatment of preeclampsia.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Perinatal Medicine Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Perinatal Medicine Year: 2021 Type: Article