Your browser doesn't support javascript.
loading
A preclinical animal study on a novel detachable endoscopic anastomosis clip for stomach perforation (with video) / 中华消化内镜杂志
Chinese Journal of Digestive Endoscopy ; (12): 471-474, 2021.
Article in Chinese | WPRIM | ID: wpr-912138
ABSTRACT

Objective:

To evaluate the safety and efficacy of a novel endoscopic anastomosis clip for the stomach perforation via an animal trial.

Methods:

Six pigs were used as experimental animals, and two perforation models (10-20 mm in diameter) were created by an endoscopic needle-knife in the stomach of each pig. The perforations were then closed by the novel detachable endoscopic anastomosis clip. The animal survival and healing of the lesions were recorded. All the clips were taken out 30 days after operation through endoscopy. Half of the animals were immediately after clip extraction and the other half of the animals survived for another 30 days owing to observation.

Results:

All clips were implanted successfully and all lesions healed during 30 days after the operation. All animals survived. The clip natural shedding rate was 33.3%(4/12), and the rest of clips were successfully disassembled and removed. All animals were alive 30 days after clip removal with lesions healed.

Conclusion:

The novel anastomosis clip is safe and effective in animal experiments with easy to operate. It could be recommended for further clinical research with good clinical prospect.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Digestive Endoscopy Year: 2021 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Digestive Endoscopy Year: 2021 Type: Article