Emphasis on the biomarkers of liver diseases and the application of its algorithm application: practice and prospect / 中华检验医学杂志

ABSTRACT

Circulation biomarker detection is one of the most feasible options for disease screening and monitoring. Focusing on the biomarkers of end stage liver diseases (liver cirrhosis and hepatocellular carcinoma), this article summarized the classification of biomarkers, the exploration and translation of new biomarkers, as well as the applications of the algorithms of the biomarkers. The key points involved in both new biomarker exploration and algorithm construction were addressed. The comprehensive application of available markers, using algorithms, is strongly recommended and should be strengthened in the future for precise clinical management and high-risk predictions in diseases such as hepatocellular carcinoma.