Clearance of Actinic Keratosis Caused by the Prodrug of 5-Fluorouracil / 대한피부과학회지
Korean Journal of Dermatology
;
: 1528-1531, 1999.
Article
in Korean
| WPRIM
| ID: wpr-91440
ABSTRACT
Tegafur [1-(tetrahydro-2-furyl)-5-fluorouracil], the prodrug of 5-fluorouracil, is an anticancer agent. Several cutaneous reactions have been reported following systemic 5-fluorouracil for the treatment of malignancies. We report a patient with marked inflammation of the actinic keratosis following the use of tegafur for stomach carcinoma. The side-effect with 5-fluorouracil was beneficial as most actinic keratosis cleared following the inflammatory reaction. Dermatologists and oncologists should be aware of this potential side-effect, not only because it may become more prevalent but, most importantly, because it is not an allergic reaction to 5-fluorouracil but a dose-dependent response, and the chemotherapy may be continued in most patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach
/
Tegafur
/
Actins
/
Drug Therapy
/
Keratosis, Actinic
/
Fluorouracil
/
Hypersensitivity
/
Inflammation
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1999
Type:
Article
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