TTF1-positive SMARCA4/BRG1 deficient lung adenocarcinoma
Journal of Pathology and Translational Medicine
;
: 53-56, 2022.
Article
in English
| WPRIM
| ID: wpr-915803
ABSTRACT
SMARCA4/BRG1-deficient lung adenocarcinoma (SD-LUAD) is being recognized as a distinct subtype based on subtle differences in its clinical, morphological, and immunophenotypic attributes compared to other non–small cell lung carcinomas. We present here a case of SD-LUAD with curious thyroid transcription factor 1 (TTF1) expression in a morphologically heterogenous lung adenocarcinoma. The better differentiated area showed preservation of TTF1 expression, and a poorly differentiated tumor had loss of TTF1 expression with universal BRG1 loss.
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Journal of Pathology and Translational Medicine
Year:
2022
Type:
Article
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