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TTF1-positive SMARCA4/BRG1 deficient lung adenocarcinoma
Journal of Pathology and Translational Medicine ; : 53-56, 2022.
Article in English | WPRIM | ID: wpr-915803
ABSTRACT
SMARCA4/BRG1-deficient lung adenocarcinoma (SD-LUAD) is being recognized as a distinct subtype based on subtle differences in its clinical, morphological, and immunophenotypic attributes compared to other non–small cell lung carcinomas. We present here a case of SD-LUAD with curious thyroid transcription factor 1 (TTF1) expression in a morphologically heterogenous lung adenocarcinoma. The better differentiated area showed preservation of TTF1 expression, and a poorly differentiated tumor had loss of TTF1 expression with universal BRG1 loss.
Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Journal of Pathology and Translational Medicine Year: 2022 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Journal of Pathology and Translational Medicine Year: 2022 Type: Article