Randomization in clinical studies / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 221-232, 2019.
Article
in English
| WPRIM
| ID: wpr-917486
ABSTRACT
Randomized controlled trial is widely accepted as the best design for evaluating the efficacy of a new treatment because of the advantages of randomization (random allocation). Randomization eliminates accidental bias, including selection bias, and provides a base for allowing the use of probability theory. Despite its importance, randomization has not been properly understood. This article introduces the different randomization methods with examples simple randomization; block randomization; adaptive randomization, including minimization; and response-adaptive randomization. Ethics related to randomization are also discussed. The study is helpful in understanding the basic concepts of randomization and how to use R software.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
English
Journal:
Korean Journal of Anesthesiology
Year:
2019
Type:
Article
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