Total Cholesterol Level for Assessing Pancreatic Insufficiency Due to Chronic Pancreatitis
Gut and Liver
;
: 563-568, 2014.
Article
in English
| WPRIM
| ID: wpr-91769
ABSTRACT
BACKGROUND/AIMS:
To determine the nutritional markers important for assessing the degree of pancreatic insufficiency due to chronic pancreatitis in routine clinical practice.METHODS:
A total of 137 patients with chronic pancreatitis were followed up for more than 1 year. They were divided into two groups a pancreatic diabetes mellitus (DM) group, consisting of 47 patients undergoing medical treatment for DM of pancreatic origin, and a nonpancreatic DM group, consisting of 90 other patients (including 86 patients without DM). Serum albumin, prealbumin, total cholesterol, cholinesterase, magnesium, and hemoglobin were compared between the two groups.RESULTS:
The total cholesterol was significantly lower in the pancreatic than the nonpancreatic DM group (164 mg/dL vs 183 mg/dL, respectively; p=0.0028). Cholinesterase was significantly lower in the former group (263 U/L vs 291 U/L, respectively; p=0.016). Among the 37 patients with nonalcoholic pancreatitis, there was no difference in the cholinesterase levels between the pancreatic and nonpancreatic (296 U/L vs 304 U/L, respectively; p=0.752) DM groups, although cholesterol levels remained lower in the former (165 mg/dL vs 187 mg/dL, respectively; p=0.052).CONCLUSIONS:
Cholinesterase levels are possibly affected by concomitant alcoholic liver injury. The total cholesterol level should be considered when assessing pancreatic insufficiency due to chronic pancreatitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreas
/
Exocrine Pancreatic Insufficiency
/
Serum Albumin
/
Cholesterol
/
Nutritional Status
/
Cholinesterases
/
Follow-Up Studies
/
Pancreatitis, Alcoholic
/
Diabetes Mellitus, Type 2
/
Pancreatitis, Chronic
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
Gut and Liver
Year:
2014
Type:
Article
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