Your browser doesn't support javascript.
loading
The Status and Treatment Outcomes in Patients with Hypopharyngeal Cancer: A Nationwide Population-based Study / 대한두경부종양학회지
Korean Journal of Head and Neck Oncology ; (2): 19-24, 2021.
Article in Korean | WPRIM | ID: wpr-917698
ABSTRACT
Background/Objectives@#The aim of this national population-based retrospective study was to analyze the status and treatment outcome in patients with hypopharyngeal cancer.Materials &

Methods:

Participants were included in the KNHIS national sample cohort who received a KNHIS health check-up in 2008 and 2009, and we followed these individuals until 2017. Patients were defined as having hypopharynx cancer if they had admissions records for hypopharynx cancer in their national health insurance data from 2010 to 2017. @*Results@#The study cohort included 3,922 patients. According to our nationwide data, 3,533(90.1%) were male with a median age of 65.03±11.04 years at the time of diagnosis. Among parametric models for hypopharyngeal cancer prognosis, old age (Hazard ratio [HR]1.92; 95% confidence interval[CI]1.76-2.09), female (HR0.77; 95% CI0.66-0.89), and low socioeconomic status (HR1.216; 95% CI1.114-1.327) were significantly associated with survival. Compared with concurrent chemoradiotherapy, patients who received no treatment (HR, 1.88; 95% CI, 1.31-2.70), neoadjuvant chemotherapy followed by surgery (HR, 1.21; 95% CI, 1.04-1.41), and chemotherapy alone (HR, 1.16; 95% CI, 1.03-1.27) showed poor prognosis in hypopharyngeal cancer. @*Conclusion@#Our data indicated that age, sex, and income were significant predictors of lifetime survival in patients with hypopharyngeal cancer. Treatment modalities were also associated with prognosis. The data have implications for treatment investigations and prevention strategies.
Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study / Prognostic study Language: Korean Journal: Korean Journal of Head and Neck Oncology Year: 2021 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Type of study: Observational study / Prognostic study Language: Korean Journal: Korean Journal of Head and Neck Oncology Year: 2021 Type: Article