Evaluation of Pattern Reversal Retinal Potential and Visually Evoked Potentiais In Ocular Hypertension and Giaucoma

ABSTRACT

The human pattern reversal retinal potential(PRRP) is a bioelectrical response that reflects neural activity generated in the proximal retina. Visual diseases which affect the retinal ganglion cells and the optic nerve often produce signifjcant reductions in the amplitude of the PRRP. PRRP amplitude reductions are freguently obseved in the patients with primary open angle glaucoma. This study was designed to determine whether patients with ocular hypertension whieh are at risk of developing glaucoma also exhibit PRRP amplitude reductions. 1. As compared to the control group the glaucoma patients showed decreased P1-N2 amplitude and a significant delay of Visual evoked potential(VEP) latency. The retinocortical time was delayed(72%) and PRRP P1-N2 amplitude was decreased in 30 percents of the ocular hypertensive patients. 2. In the glaucoma and ocular hypertension, VEP P1 latency has more diagnoic value than PRRP P1 latency. 3. VEP and PRRP show more diagnostic values and these tests are essential for early diagnosis in the glaucoma.