Association between Depressive Symptoms and Vitamin D Deficiency in Adults with Overweight or Obesity / 우울ㆍ조울병

ABSTRACT

Background@#The relationship between a low vitamin D level and depression has been demonstrated repeatedly. We assessed the correlation between vitamin D status and the prevalence of depression according to body weight status. @*Methods@#Data from 1,747 participants who took part in the 2014 Korean National Health and Nutrition Examination Survey were analyzed. The presence of depression was identified by the brief, self-reported Patient Health Questionnaire-9 (PHQ-9), vitamin D status was defined based on the serum 25-hydroxyvitamin D [25(OH)D] level, and body weight status was expressed as the body mass index. @*Results@#After adjusting for potential confounding factors, participants in the vitamin D deficiency group (odds ratio [OR], 2.70; 95% confidence interval [CI], 1.01-7.20) and severe deficiency group (OR, 2.89; 95% CI, 1.04-8.00) were significantly more likely to experience depression. Multivariate logistic regression analyses indicated that among the participants with overweight or obesity, those in the vitamin D deficiency group were 3.71 times more likely than those in the sufficiency group (OR, 3.71; 95% CI, 1.08-12.74) to experience depression. @*Conclusion@#Our findings suggest a significant association between low vitamin D levels and depression in adults with overweight or obesity. Further studies are needed to elucidate the association between vitamin D status and depression according to body weight status.