Risk Factors for Local Tumor Recurrence after Segmental Transarterial Chemoembolization for Hepatocellular Carcinoma: the Importance of Tumor Located in the Segmental Border Zone
Korean Journal of Radiology
;
: 267-274, 2006.
Article
in English
| WPRIM
| ID: wpr-91961
ABSTRACT
OBJECTIVE:
We wanted to evaluate whether tumors located in a segmental border zone are predisposed to local recurrence after performing segmental transarterial chemoembolization for hepatocellular carcinoma. MATERIALS ANDMETHODS:
Seventy-three hepatocellular carcinoma nodules were retrospectively analyzed for local tumor recurrence after performing segmental transarterial chemoembolization by using follow-up CT studies (median follow-up period 20 months, range 4-77 months). The tumors were divided into two groups according to whether the lesions were located at the segmental border zone (Group I) or not (Group II). Comparison of the tumor characteristics and chemoembolization methods between the two groups was performed using the chi-square test. The local recurrence rates were compared by Kaplan-Meyer method and analyzed with the log rank test.RESULTS:
Local tumor recurrence occurred for 25 hepatocellular carcinoma nodules (42.9%). The follow-up periods, tumor characteristics and chemoembolization methods between Groups l and ll were comparable. The local recurrence rate was 64.0% (16/25) in Group I and 18.8% (9/48) in Group II. The difference was statistically significant on the univariate and multivariate analyses (p = 0.000 for both).CONCLUSION:
Tumor location in a segmental border zone was a significant risk factor for local tumor recurrence after performing segmental transarterial chemoembolization for hepatocellular carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Doxorubicin
/
Chi-Square Distribution
/
Proportional Hazards Models
/
Retrospective Studies
/
Risk Factors
/
Chemoembolization, Therapeutic
/
Iodized Oil
/
Carcinoma, Hepatocellular
/
Liver Neoplasms
/
Neoplasm Recurrence, Local
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Radiology
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS