Antimicrobial Effect of Photodynamic Therapy Using Plaque Disclosing Agent / 대한소아치과학회지
Journal of Korean Academy of Pediatric Dentistry
;
(4): 120-127, 2020.
Article
in Korean
| WPRIM
| ID: wpr-919843
ABSTRACT
The aim of this study was to evaluate the antimicrobial effect of photodynamic therapy (PDT) using plaque disclosing agent, 10 - 20 mM erythrosine, as a photosensitizer.Multispecies cariogenic biofilms containing Streptococcus mutans , Lactobacillus casei and Candida albicans were formed on hydroxyapatite disc. 20 μM, 10 mM and 20 mM erythrosine were applied as a photosensitizer for 3 minutes, and then light-emitting diode (LED) irradiated for 24 seconds. Colony-forming unit (CFU) were measured and biofilms were observed using confocal laser scanning microscopy (CLSM). CFU were significantly decreased in the PDT groups using 10 - 20 mM erythrosine (10 mM, 20mM) and the results were also confirmed by CLSM.This study confirms the high antimicrobial effect of photodynamic therapy using plaque disclosing agent as a photosensitizer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Korean
Journal:
Journal of Korean Academy of Pediatric Dentistry
Year:
2020
Type:
Article
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