Logopenic Progressive Aphasia Revealing Positive Cerebrospinal Fluid Biomarkers for Alzheimer's Disease
Journal of the Korean Neurological Association
;
: 98-102, 2014.
Article
in Korean
| WPRIM
| ID: wpr-91986
ABSTRACT
Primary progressive aphasia (PPA) is classified into agrammatic, semantic, and logopenic variants, but differential diagnosis is often challenging. There is accumulating evidence that the neuropathology of logopenic PPA is distinct from that of the other types. We report herein a woman with logopenic PPA who was diagnosed by clinical, neuropsychological, and radiologic data during 2 years of follow-up. Interestingly, her cerebrospinal fluid biomarkers were found to be similar to those found in Alzheimer's disease, with a decreased concentration of Abeta42 and an increased concentration of pTau181 (tTau).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aphasia
/
Semantics
/
Biomarkers
/
Cerebrospinal Fluid
/
Follow-Up Studies
/
Aphasia, Primary Progressive
/
Diagnosis, Differential
/
Alzheimer Disease
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
2014
Type:
Article
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