Two Cases of Localized Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Manifested with Intractable Otitis Media / 대한이비인후과학회지

ABSTRACT

Localized form of myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis (MPO-AAV) in the ear is a rare disease. It manifests as a sudden otalgia with hearing loss accompanied by dizziness and facial nerve palsy. Early diagnosis and treatment with immunosuppressive agents are important to prevent the irreversible progression of sensorineural hearing loss. However, it is hard to diagnose AAV because it can be confused with other common otologic disease, such as acute otitis media or middle ear effusion with labyrinthitis. Here, we report two cases of localized form of MPO-AAV manifesting otologic symptoms that have been properly diagnosed and treated with steroid and immunosuppressant.