Application of bioisostere-bicyclo [1.1.1] pentane (BCP) in drug design / 中国药科大学学报
Journal of China Pharmaceutical University
;
(6): 1-9, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-920643
ABSTRACT
@#With the development of medicinal and organic chemistry, more and more classical and non-classical bioisosteres are used in the design of novel drugs.Bicyclo[1.1.1] pentane (BCP), as a bioisostere of benzene, t-butyl and alkyne moieties,has recently received extensive attention from medicinal and organic chemists.This paper briefly reviews its application in drug design to provide reference for drug discovery researchers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of China Pharmaceutical University
Year:
2022
Type:
Article
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