Computed tomography-identified phenotypes of small airway obstructions in chronic obstructive pulmonary disease / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 2025-2036, 2021.
Article
in English
| WPRIM
| ID: wpr-921118
ABSTRACT
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characteristic of small airway inflammation, obstruction, and emphysema. It is well known that spirometry alone cannot differentiate each separate component. Computed tomography (CT) is widely used to determine the extent of emphysema and small airway involvement in COPD. Compared with the pulmonary function test, small airway CT phenotypes can accurately reflect disease severity in patients with COPD, which is conducive to improving the prognosis of this disease. CT measurement of central airway morphology has been applied in clinical, epidemiologic, and genetic investigations as an inference of the presence and severity of small airway disease. This review will focus on presenting the current knowledge and methodologies in chest CT that aid in identifying discrete COPD phenotypes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Pulmonary Emphysema
/
Tomography, X-Ray Computed
/
Pulmonary Disease, Chronic Obstructive
/
Airway Obstruction
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Chinese Medical Journal
Year:
2021
Type:
Article
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