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Effectiveness of azithromycin mass drug administration on trachoma: a systematic review / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 2944-2953, 2021.
Article in English | WPRIM | ID: wpr-921173
ABSTRACT
BACKGROUNDS@#Azithromycin mass drug administration (MDA) is a key part of the strategy for controlling trachoma. This systematic review aimed to comprehensively summarize the present studies of azithromycin MDA on trachoma; provide an overview of the impact of azithromycin MDA on trachoma in different districts; and explore the possible methods to enhance the effectiveness of azithromycin MDA in hyperendemic districts.@*METHODS@#PubMed, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, and ClinicalTrials.gov were searched up to February 2021 with no language restriction. Studies reporting the effect of azithromycin MDA on trachoma were included. Mathematical modeling studies, animal studies, case reports, and reviews were excluded. The trachomatous inflammation-follicular (TF) 30.0%), especially with baseline TF >50.0%, annual MDA was unable to achieve the TF 10.0% is not appropriate for all eligible districts.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Trachoma / Prevalence / Azithromycin / Mass Drug Administration / Anti-Bacterial Agents Type of study: Prevalence study / Systematic reviews Limits: Humans / Infant Language: English Journal: Chinese Medical Journal Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Trachoma / Prevalence / Azithromycin / Mass Drug Administration / Anti-Bacterial Agents Type of study: Prevalence study / Systematic reviews Limits: Humans / Infant Language: English Journal: Chinese Medical Journal Year: 2021 Type: Article