Effects of different irradiators on the establishment of osteoradionecrosis model of rat mandible / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 524-530, 2021.
Article
in English
| WPRIM
| ID: wpr-921369
ABSTRACT
OBJECTIVES@#To compare the effects of different irradiators on the establishment of osteoradionecrosis of jaw model (ORNJ) to explore an ideal modeling method.@*METHODS@#A total of 33 adult SD rats were included and randomly divided into three groups according to the radiation equipment, namely, the blank control (CN, 3 rats), group A (linear accelerator irradiation, 15 rats), and group B (small-animal irradiator irradiation, 15 rats). Groups A and B were irradiated with daily fractions of 7, 8, and 9 Gy for 5 days and further divided into three subgroups as follows group A@*RESULTS@#At 3 weeks after dental extractions, complete gingival healing was found in the regions of dental extractions in groups A@*CONCLUSIONS@#Small-animal irradiator irradiation is an ideal device for establishing ORNJ model.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoradionecrosis
/
Rats, Sprague-Dawley
/
X-Ray Microtomography
/
Mandible
/
Molar
Limits:
Animals
Language:
English
Journal:
West China Journal of Stomatology
Year:
2021
Type:
Article
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