Vaginal microbiota transplantation for treatment of bacterial vaginosis: a review / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 3820-3827, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-921468
ABSTRACT
Bacterial vaginosis (BV) is a disease caused by vaginal microbiota dysbiosis. The conventional antibiotic treatment can aggravate microbial dysbiosis, alter the acid environment of the vagina and lead to drug resistance, thus shows low cure rate and high recurrence rate. This poses significant physiological and psychological burden to the BV patients. Vaginal microbiota transplantation (VMT) is a novel live biotherapeutic approach. It directly engrafts the whole vaginal microbiota from healthy women to the vaginal tract of patients to rapidly reconstruct the vaginal microbiota environment and restore the vaginal health. This article summarizes the development, present challenges, and future directions of using VMT, with the aim to explore new strategies for treatment of BV and promote the clinical use of VMT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vagina
/
Vaginosis, Bacterial
/
Dysbiosis
/
Microbiota
Limits:
Female
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2021
Type:
Article
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