Advances of Cas9/sgRNA delivery system for gene editing / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 3880-3889, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-921473
ABSTRACT
In the application of CRISPR genome editing, direct cellular delivery of non-replicable Cas9/sgRNA may reduce unwanted gene targeting and integrational mutagenesis, thus offering greater specificity and safety. Cas9/sgRNA delivery system holds great potential for treating genetic diseases. This review summarizes the advances of Cas9/sgRNA delivery systems and its therapeutic applications, providing new understandings and inspirations for vector design and future clinical applications.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
CRISPR-Cas Systems
/
Gene Editing
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2021
Type:
Article
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