Correlation of B-type Natriuretic Peptide Level with Hemodynamic Parameters and Inflammatory Cytokines in Patients with Gram-negative Sepsis / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 879-885, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-921554
ABSTRACT
Objective To study the correlation of B-type natriuretic peptide(BNP)level with hemodynamic parameters and inflammatory cytokines in patients with Gram-negative sepsis,and further determine the main factors for the significant increase of BNP level. Methods The prospective study method was applied,and septic patients infected with Gram-negative bacteria from May 2017 to October 2019 were enrolled.The patients were divided into the BNP<2400 ng/L group and the BNP≥2400 ng/L group by taking the average value of BNP as the dividing point.The independent predictors of BNP≥2400 ng/L were analyzed by Logistic regression.Pearson correlation analysis was used to analyze the correlation between BNP and various indicators. Results A total of 106 patients with Gram-negative sepsis were included,among which 60 cases present with higher serum BNP levels than the average of(2398.45 ± 421.45)ng/L.Thus BNP≥2400 ng/L was considered as a significantly increased BNP level.Multiple logistic regression analysis showed that cardiac index(CI)[odds ratio (
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Stroke Volume
/
Prospective Studies
/
Cytokines
/
Ventricular Function, Left
/
Gram-Negative Bacterial Infections
/
Sepsis
/
Natriuretic Peptide, Brain
/
Hemodynamics
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2021
Type:
Article
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