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A new cembranoid diterpene from Olibanum / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 6417-6421, 2021.
Article in Chinese | WPRIM | ID: wpr-921801
ABSTRACT
Five compounds were isolated from the alcohol extract of Olibanum by MCI, silica gel, ODS, and Sephadex LH-20 column chromatographies and preparative high-performance liquid chromatography(HPLC). On the basis of spectral data and literature data, the compounds were identified as(1S,3R,4S,7R,11S,12R)-112,47-diepoxisonane-8(19)-ene-3,11-diol(1), boscartin A(2),(+)-resinolin(3),(+)-5-hydroxy-3,4-dimethyl-5-pentylfuran-2(5H)-one(4), and acerogenin A(5). Compound 1 is a new compound, and compounds 3-5 were isolated from Olibanum for the first time. The structure of compound 1 was determined by spectroscopic analysis and single-crystal X-ray diffraction. Compounds 1 and 2 were tested for PC12 neurotoxicity, and the results showed that they were both safe compounds.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Molecular Structure / Chromatography, High Pressure Liquid / Diterpenes / Frankincense Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Molecular Structure / Chromatography, High Pressure Liquid / Diterpenes / Frankincense Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2021 Type: Article