Research progress on screening of pregnancy-related diseases based on fetal cell free DNA / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 1025-1029, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-921991
ABSTRACT
Fetal cell free DNA (cfDNA) in maternal blood circulation mainly originates from placental trophoblasts which have dual characteristics of apoptotic cells and the embryo, and can be affected by maternal factors. Pregnancy-related diseases including preeclampsia, gestational diabetes mellitus, preeclampsia, macrosomia and fetal growth restriction can seriously affect maternal health and pregnancy outcome. Early prediction and timely intervention are important means to reduce the risk. Fetal cfDNA and prediction of pregnancy-related diseases have become a hot topicfor current research. This paper reviews the latest progress made in the field.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Placenta
/
Pregnancy Complications
/
Pregnancy Outcome
/
Fetus
/
Cell-Free Nucleic Acids
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Female
/
Humans
/
Pregnancy
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2021
Type:
Article
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