The role of retinoic acid in the commitment to meiosis / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 549-554, 2021.
Article
in English
| WPRIM
| ID: wpr-922374
ABSTRACT
Male meiosis is a complex process whereby spermatocytes undergo cell division to form haploid cells. This review focuses on the role of retinoic acid (RA) in meiosis, as well as several processes regulated by RA before cell entry into meiosis that are critical for proper meiotic entry and completion. Here, we discuss RA metabolism in the testis as well as the roles of stimulated by retinoic acid gene 8 (STRA8) and MEIOSIN, which are responsive to RA and are critical for meiosis. We assert that transcriptional regulation in the spermatogonia is critical for successful meiosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spermatogenesis
/
Tretinoin
/
Cell Differentiation
/
Meiosis
Limits:
Animals
/
Humans
Language:
English
Journal:
Asian Journal of Andrology
Year:
2021
Type:
Article
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