Physical and neuropsychological development of children with Citrin deficiency / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 1262-1266, 2021.
Article
in En
| WPRIM
| ID: wpr-922419
Responsible library:
WPRO
ABSTRACT
OBJECTIVES@#To study the physical and neuropsychological development of children with Citrin deficiency (CD).@*METHODS@#A total of 93 children, aged 1.9-59.8 months, who were diagnosed with CD by @*RESULTS@#For the 93 children with CD, the incidence rate of failure to thrive was 25% (23 children) and the proportion of small for gestational age was 47% (44 children). For the 100 cases of CD, the incidence rates of growth retardation, underweight, emaciation, overweight, and microcephalus were 23% (23 cases), 14% (14 cases), 4% (4 cases), 8% (8 cases), and 9% (9 cases), respectively. The incidence rate of neuropsychological developmental delay was 25% (25 cases), and the incidence rates of development delay in the five domains of adaptability, gross motor, fine motor, language, and social ability were 7% (7 cases), 15% (15 cases), 7% (7 cases), 9% (9 cases), and 7% (7 cases), respectively.@*CONCLUSIONS@#Physical and neuropsychological developmental delay can be observed in children with CD, and physical and neuropsychological development should be regularly assessed.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Retrospective Studies
/
Citrullinemia
/
Mitochondrial Membrane Transport Proteins
Type of study:
Observational_studies
Limits:
Child
/
Humans
/
Infant
Language:
En
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2021
Type:
Article