Pure photosensitizer-driven nanoassembly with core-matched PEGylation for imaging-guided photodynamic therapy
Acta Pharmaceutica Sinica B
;
(6): 3636-3647, 2021.
Article
in English
| WPRIM
| ID: wpr-922430
ABSTRACT
Pure drug-assembled nanomedicines (PDANs) are currently under intensive investigation as promising nanoplatforms for cancer therapy. However, poor colloidal stability and less tumor-homing ability remain critical unresolved problems that impede their clinical translation. Herein, we report a core-matched nanoassembly of pyropheophorbide a (PPa) for photodynamic therapy (PDT). Pure PPa molecules are found to self-assemble into nanoparticles (NPs), and an amphiphilic PEG polymer (PPa-PEG
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Acta Pharmaceutica Sinica B
Year:
2021
Type:
Article
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