Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury
Acta Pharmaceutica Sinica B
;
(6): 3857-3868, 2021.
Article
in English
| WPRIM
| ID: wpr-922446
ABSTRACT
Drug-induced liver injury (DILI) is a leading reason for preclinical safety attrition and post-market drug withdrawals. Drug-induced mitochondrial toxicity has been shown to play an essential role in various forms of DILI, especially in idiosyncratic liver injury. This study examined liver injury reports submitted to the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) for drugs associated with hepatotoxicity
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Acta Pharmaceutica Sinica B
Year:
2021
Type:
Article
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