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Clinical features of 44 patients with small bowel Crohn / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 1109-1113, 2021.
Article in English | WPRIM | ID: wpr-922591
ABSTRACT
OBJECTIVES@#At present, there are many studies on Crohn's disease of terminal ileum and colon, but few studies on Crohn's disease of small intestine alone. This study aims to analyze the clinical features and therapeutic effect of small bowel in adult patients with Crohn's disease so as to strengthen the diagnosis and treatment for this disease.@*METHODS@#From July 1, 2015 to October 31, 2018, patients with small bowel Crohn's disease at Department of Gastroenterology, Third Xiangya Hospital of Central South University, were enrolled. At the same time, patients' demographics and clinical data were collected.@*RESULTS@#A total of 44 patients were small bowel Crohn's disease. Among them, 40 patients were male. The age at diagnosis was (35.8±10.3) years old and disease duration was (35.2±59.5) months. The subtypes included 29(65.9%) of ileum, 7(15.9%) of jejunum, 8(18.2%) of ileum with jejunum. There were 27(61.4%) of stricture behavior, 4(9.1%) of penetrating behavior, and 13(29.5%) of non-stricture and non-penetrating behavior. Endoscopic visible stricture (29/85, 34.1%) was common, followed by longitudinal ulcers (27/85, 31.8%). Non-caseate granulomatous were found in 2 cases (4.5%). The score of Crohn's disease activity index was correlated to hemoglobin, hematocrit, and erythrocyte sedimentation rate (all @*CONCLUSIONS@#Patients with ileum account for a large proportion in patients with small bowel Crohn's disease. Stricture is more common in small bowel Crohn's disease. Stricture and longitudinal ulcer are more common under enteroscopy. Crohn's disease activity index is correlated to hemoglobin, red blood cell specific volume, and erythrocyte sedimentation rate. The most common complication is intestinal obstruction. Mesalazine is less effective on small bowel Crohn's disease.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Crohn Disease / Endoscopy, Gastrointestinal / Ileum / Intestinal Obstruction / Intestine, Small Limits: Adult / Humans / Male Language: English Journal: Journal of Central South University(Medical Sciences) Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Crohn Disease / Endoscopy, Gastrointestinal / Ileum / Intestinal Obstruction / Intestine, Small Limits: Adult / Humans / Male Language: English Journal: Journal of Central South University(Medical Sciences) Year: 2021 Type: Article