Clinical Analysis on 200 Cases of Kidney Transplantation in a Single Center / 대한이식학회지

ABSTRACT

PURPOSE: To determine the risk factors relating renal allograft and patient survival, we, Dae Jeon St. Mary's Hospital transplantaion team, Dae Jeon, Korea, reviewed 200 cases of kidney transplantation. METHODS: 200 medical records of kidney transplantation from February 1988 to June 2000 was reviewed retrospectively. The clinical follow up period was February 2001, and clinical analysis was done. RESULTS: 1) The original renal disease of the cases were 78 cases of chronic glomerulonephritis, 18 cases of diabetic nephropathy, 16 cases of hypertensive nephrosclerosis and 1 case of lupus nephritis, 2) The recipient-donor relationships were 14 cases of parent to offspring, 9 cases of offspring to parents, 26 cases of between siblings. There were 150 cases of non- related donor and 1 case of cadaveric donor, 3) At the end of Feb. 2001, 33 graft and 10 patients were lost (5 year graft survival was 88.3% and 5 year patient survival rate was 94.6%), 4) 7 cases of malignant tumors, 171 cases of hypertension, 141 cases of hyperlipdemia, 76 cases of Cushing's disease and 58 cases of hyperuricemia were developed, 5) There were 114 cases of infections (41 cases of bacterial infections, 40 cases of viral infections, 13 cases of tuberculosis and 20 cases of fungal infections), 6) The cases of surgical complications were 16 cases of lymphocele, 9 cases of urinary leakage, 5 cases of hematome and other 3 cases, 7) The factor analysis for graft survival showed that the donor and recipient age, number of acute rejection episodes had statistical significance. CONCLUSION: Episodes of acute rejection and old age group both in donor and recipient over 50 were the risk factors affecting renal allograft survival.