Analysis of hyperuricemia and its risk factors in male pilots / 中国职业医学

ABSTRACT

OBJECTIVE: To analyze the prevalence and risk factors of hyperuricemia in male pilots.METHODS: By using the convenient sampling method, 1 561 male pilots were selected as the study subjects. Among them, 678 patients with hyperuricemia were taken as the observation group, and 883 pilots without hyperuricemia were taken as the control group. The incidence of hyperuricemia in the two groups was compared. RESULTS: The prevalence of hyperuricemia in male pilots was 43.4%(678/1 561). The pilots in the observation group had higher body mass index(BMI), higher triglyceride(TG), lower high-density lipoprotein cholesterol, higher low-density lipoprotein cholesterol(LDL-C), higher mixed hyperlipidemia and higher non-alcoholic fatty liver disease(NAFLD)(all P<0.05) compared with the control group. The result of multivariate logistic regression analysis showed that high BMI, high TG, high LDL-C and NAFLD were the risk factors for hyperuricemia in male pilots(odds ratios were 1.517, 1.559, 1.384 and 1.782, respectively, all P<0.01), while age≥40 was a protective factor for hyperuricemia(odds ratio was 0.593, P<0.01).CONCLUSION: The prevalence of hyperuricemia in male pilots is relatively high. The prevention and treatment of hyperuricemia in pilots should be strengthened.