Clinical management guidelines for acute fatty liver of pregnancy in China (2022) / 临床肝胆病杂志

ABSTRACT

Acute fatty liver of pregnancy (AFLP) is a rare but critical obstetric disease with a high mortality rate, and it poses a serious threat to the safety of the mother and the child. The guidelines are developed to standardize clinical management and improve the outcome of the mother and the child. Based on multiple previous clinical questionnaire surveys, the guideline development group identified the nine clinical issues that clinicians are most concerned with and gave recommendations for each issue, including the outpatient screening for AFLP, diagnosis, preoperative risk assessment, selection of mode of delivery, selection of anesthesia method, perinatal complications, indication for artificial liver therapy, evaluation of prognosis, and monitoring during treatment, which covers the hot topics associated with the diagnosis and treatment of AFLP.