Glial Choristoma in the Middle Ear and Mastoid Bone: A Case Report
Journal of Korean Medical Science
;
: 155-158, 2004.
Article
in English
| WPRIM
| ID: wpr-92396
ABSTRACT
Heterotopic brain tissue usually involves extracranial midline structures of the head and neck such as nose, nasopharynx, and oral cavity. Its occurrence in the non-midline structures, including middle ear, is rare. We described a 50-yr-old-man with heterotopic glial tissue in the middle ear and mastoid bone. The patient presented with progressive hearing loss for 8 yr. There was no history of congenital anomalies, trauma, or ear surgery. Computed tomography revealed a mass-like lesion with soft tissue density occupying the middle ear cavity and mastoid antrum. At the operation, a graywhite fibrotic mass was detected in the epitympanic area. Mesotympanum and ossicles were intact. The patient underwent left simple mastoidectomy with type I tympanoplasty. During operation, definite cranial bone defect or cerebrospinal fluid leakage was not found. Histologically, the lesion was composed of exclusively mature, disorganized glial tissue with fibrovascular elements in a rather loose fibrillary background. Glial tissue showed diffuse positive reaction for glial fibrillar acidic protein and S100 protein on immunohistochemical study.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Audiometry
/
Brain
/
Brain Diseases
/
Immunohistochemistry
/
Tomography, X-Ray Computed
/
Neuroglia
/
Choristoma
/
Ear, Middle
/
Mastoid
Limits:
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2004
Type:
Article
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