A Case of Amyloidosis with Recurrent Intestinal Bleeding / 대한소화기내시경학회지

ABSTRACT

Amyloidosis is characterized by deposition of amyloid in the intercellular space and vascular wall. Amyloid deposition provokes dysfunction of the accumulated organ and causes variable clinical symptoms that depend on the involved organ. Although intestinal bleeding may occur with amyloidosis, it is relatively rare as a presenting symptom or as the sole manifestation of the disease. We experienced a case of recurrent intestinal bleeding in a 68-year-old female patient with lambda type primary amyloidosis. A colonoscopy revealed the presence of multiple large circular ulcers in the transverse colon and nonspecific submucosal hemorrhage and edema at the rectum. An endoscopic biopsy established the diagnosis of amyloidosis. A case of recurrent intestinal bleeding in a patient with primary amyloidosis is presented, with a review of the literature.