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Cost-effectiveness of chronic hepatitis C screening and treatment
Clinical and Molecular Hepatology ; : 164-173, 2022.
Article in English | WPRIM | ID: wpr-925755
ABSTRACT
Hepatitis C virus (HCV) infection is the second most common cause of chronic liver disease in South Korea, with a prevalence ranging from 0.6% to 0.8%, and HCV infection incidence increases with age. The anti-HCV antibody test, which is cheaper than the HCV RNA assay, is widely used to screen for HCV infections; however, the underdiagnosis of HCV is a major barrier to the elimination of HCV infections. Although several risk factors have been associated with HCV infections, including intravenous drug use, blood transfusions, and hemodialysis, most patients with HCV infections present with no identifiable risk factors. Universal screening for HCV in adults has been suggested to improve the detection of HCV infections. We reviewed the cost-effectiveness of HCV screening and the methodologies used to perform screening. Recent studies have suggested that universal HCV screening and treatment using direct-acting antivirals represent cost-effective approaches to the prevention and treatment of HCV infection. However, the optimal timing and frequency of HCV screening remain unclear, and further studies are necessary to determine the best approaches for the elimination of HCV infections.
Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study / Health economic evaluation / Prognostic study / Risk factors / Screening study Language: English Journal: Clinical and Molecular Hepatology Year: 2022 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study / Health economic evaluation / Prognostic study / Risk factors / Screening study Language: English Journal: Clinical and Molecular Hepatology Year: 2022 Type: Article