Clinical Features of Neuroendocrine Lung Cancer / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 474-477, 2001.
Article
in Korean
| WPRIM
| ID: wpr-92755
ABSTRACT
PURPOSE:
This study was performed to investigate the clinical features of neuroendocrine lung cancer. MATERIALS ANDMETHODS:
We performed a retrospective review of the histopathology and clinical information of 21 patients diagnosed as having neuroendocrine lung cancer between 1995 and 1999.RESULTS:
Nineteen cases were male and 2 were female. The median age was 64 years (range 45~80). Pathologic classification were atypical carcinoid (AC) in 2 cases, large cell neuroendocrine carcinoma (LCNEC) in 7 cases, and intermediate cell neuroendocrine carcinoma (ICNC) in 12 cases. Nine patients received tumor resection as first line therapy; adjuvant chemotherapy was given to 3 patients. Concurrent chemoradiotherapy was given to 1 patient. Six patients received palliative chemotherapy. The chemotherapy regimen included etoposide cisplatin in 5 cases and vinorelbine+cisplatin in 1 case. The median survival times were 11, 16 and 59 weeks for AC, LCNEC and ICNC, respectively. The estimated 2-year survival rates were AC 0%, LCNEC 22% and ICNC 31%.CONCLUSION:
Surgery may have a positive effect on survival in patients with early stage cansers. Further investigation is required to improve survival in cases of advanced stage cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Carcinoid Tumor
/
Survival Rate
/
Retrospective Studies
/
Cisplatin
/
Classification
/
Chemotherapy, Adjuvant
/
Carcinoma, Neuroendocrine
/
Drug Therapy
/
Etoposide
/
Chemoradiotherapy
Type of study:
Observational study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Cancer Research and Treatment
Year:
2001
Type:
Article
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