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Microbial synthesis of monoterpenoids: a review / 生物工程学报
Chinese Journal of Biotechnology ; (12): 427-442, 2022.
Article in Chinese | WPRIM | ID: wpr-927720
ABSTRACT
Monoterpenoids that belong to the terpenoids family are usually volatile and have strong aroma. Some monoterpenoids also have antioxidant, antibacterial and anti-inflammatory activities, which make them important raw materials for medicine, food and cosmetics industry. In recent years, the heterologous synthesis of monoterpenoids by microorganisms has attracted extensive attention. However, its large-scale application is greatly hampered by the low yield and high production cost. Nowadays, the rapid development of synthetic biology provides new approaches for enhancing the production of monoterpenoids by microorganisms. Different kinds of recombinant strains can be obtained via engineering of microbial cells to produce a variety of monoterpenoids with different properties. This paper summarized the latest strategies and progress in the application of synthetic biology to produce monoterpenoids by microorganisms, including the design and modification of biosynthetic pathway, as well as the design and optimization of high-yield monoterpenoids producing chassis cells.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Terpenes / Monoterpenes / Biosynthetic Pathways / Synthetic Biology / Metabolic Engineering Language: Chinese Journal: Chinese Journal of Biotechnology Year: 2022 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Terpenes / Monoterpenes / Biosynthetic Pathways / Synthetic Biology / Metabolic Engineering Language: Chinese Journal: Chinese Journal of Biotechnology Year: 2022 Type: Article